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目的:探讨在4 Hz谐振频率下不同干预方式对兔抗谐振后血清代谢标志物特异性碱性磷酸酶(BALP)、6-酮前列腺素1α(6-keto-PGF 1α)及丙二醛(MDA)含量的影响。方法:75只新西兰兔随机均分为正常对照组、模型对照组及3个谐振干预实验组,每组15只,分别于实验的2、4、6周从每组随机抽取5只在清晨空腹状态下经耳缘静脉穿刺抽取5 m L静脉血,测定血清BALP、6-keto-PGF 1α及MDA含量并观察其动态变化。结果:与正常对照组和谐振干预3组比较,模型对照组、谐振干预1、2组血清BALP、6-keto-PGF 1α第4周开始升高,MDA含量从第6周开始升高且差异显著(P<0.05)。与模型对照组相比,正常对照组、谐振干预3组血清BALP、6-keto-PGF 1α和MDA的含量在第4、6周降低且谐振干预1、2组与谐振干预3组同期相比差异显著(P<0.05)。结论:不同干预对谐振引起的下腰痛早期防治具有重要参考价值,尤以PEP加工成大小不同空心棉球组成表面凹凸不平的座垫对于防治下腰痛发生具有重要意义。
OBJECTIVE: To investigate the effects of different interventions on the anti-resonance of rabbit serum specific alkaline phosphatase (BALP), 6-keto-PGF 1α and malondialdehyde MDA) content. Methods: Seventy-five New Zealand rabbits were randomly divided into normal control group, model control group and three resonance intervention experimental groups, 15 rats in each group. Five rabbits were randomly selected from each group at 2,4,6 weeks of experiment. 5 m L venous blood was collected through the ear vein and the contents of BALP, 6-keto-PGF 1α and MDA were measured and the changes of the dynamic changes were observed. Results: Compared with the normal control group and the resonant intervention group 3, the levels of serum BALP and 6-keto-PGF 1α in the model control group and the group of resonance intervention 1,2 began to increase from the 4th week to the 6th week, and the MDA content increased from the 6th week Significant (P <0.05). Compared with the model control group, the levels of serum BALP, 6-keto-PGF 1α and MDA in the normal control group and the resonance intervention group decreased at the 4th and 6th week, The difference was significant (P <0.05). Conclusion: Different interventions have important reference value for the early prevention and treatment of low back pain caused by resonance. Especially, it is of great significance to treat the low back pain with PEP processed into the uneven surface cushion with different sizes of hollow cotton balls.