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目的:筛查孕产妇乙肝病毒(HBV)感染情况,提高HBV母婴传播阻断的保护率。方法:采用酶联免疫吸附试验(ELISA)对采集孕产妇血清检测HBV标志物,相关数据经统计学处理,进行HBV感染多因素分析。结果:孕产妇HBsAg阳性率8.98%,城市孕产妇HBsAg阳性率低于农村孕产妇(P<0.01),接种乙肝疫苗孕产妇HBsAg阳性率低于未接种孕产妇(P<0.01),不同年龄、民族孕产妇之间无显著性差异;HBsAg阳性孕妇以小三阳、大三阳、HBsAg阳性伴抗-HBc阳性为主要感染模式。结论:对乙型肝炎易感的女童和育龄妇女接种乙肝疫苗可以降低孕产妇HBsAg携带率;孕妇产前筛查HBsAg有助于孕产妇保健行为和新生儿免疫。
Objective: To screen maternal hepatitis B virus (HBV) infection and improve the protection rate of mother-to-child transmission of HBV. Methods: HBV markers were detected by enzyme-linked immunosorbent assay (ELISA) in maternal serum. The data were statistically analyzed and analyzed by multivariate analysis. Results: The positive rate of HBsAg in pregnant women was 8.98%. The positive rate of HBsAg in urban pregnant women was lower than that in rural pregnant women (P <0.01). The positive rate of HBsAg in pregnant women vaccinated with hepatitis B vaccine was lower than that in unvaccinated pregnant women (P <0.01) There was no significant difference between ethnic pregnant women; HBsAg positive pregnant women with small three positive, big three positive, HBsAg positive with anti-HBc positive as the main infection pattern. Conclusion: Hepatitis B vaccination of pregnant women and women who are susceptible to hepatitis B can reduce the carrier rate of HBsAg in pregnant women; Prenatal screening of pregnant women HBsAg contribute to maternal health behaviors and neonatal immunization.