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1182例初治肺结核患者采用短疗程抗结核药物治疗方案。甲组404例采用异菸肼+链霉素+吡嗪酰胺/日;链霉素+异菸肼+吡嗪酰胺/每周3次或链霉素+异菸肼+吡嗪酰胺/每周2次,疗程6或9个月,结果41例细菌学复发。乙组778例采用链霉素+异菸肼/日或链霉素+异菸肼+氨硫脲/日或链霉素+异菸肼+吡嗪酰胺/日或链霉素+异菸肼+利福平/日,疗程6个月,结果68例细菌学复发。两组复发患者的结核菌对链霉素和异菸肼仍敏感。甲组28例和乙组45例再用一线抗结核药物进行复治观察。
1182 newly diagnosed tuberculosis patients treated with a short course of anti-TB drug treatment. A group of 404 cases with isoniazid + streptomycin + pyrazinamide / day; streptomycin + isoniazid + pyrazinamide / 3 times a week or streptomycin + isoniazid + pyrazinamide / week 2 times, 6 or 9 months course of treatment, the results of 41 cases of bacteriological recurrence. Group B 778 cases with streptomycin + isoniazid / day or streptomycin + isoniazid + thiosemicarbazone / day or streptomycin + isoniazid + pyrazinamide / day or streptomycin + isoniazid + Rifampicin / day, treatment for 6 months, the results of 68 cases of bacteriology recurrence. Mycobacterium tuberculosis is still sensitive to streptomycin and isoniazid in both groups. 28 cases in group A and 45 cases in group B were treated with first-line anti-tuberculosis drugs for retreatment again.