妊娠肝内胆汁淤积症(intrahepatic cholestasis ofpregnan-cy,ICP)是妊娠期特有的疾病,以瘙痒、黄疸为主要症状,并有胆酸、肝酶升高等生化指标异常。ICP患者的预后良好,但对胎儿有不良影响,可导致早产、胎儿窘迫及胎死宫内等,使围产儿病发率、病死率及早产率增高,属高危妊娠范 Intrahepatic cholestasis of pregnancy (ICP) is a peculiar disease during pregnancy, with pruritus and jaundice as the main symptoms, and abnormal biochemical indexes such as bile acid and elevated liver enzymes. ICP patients with good prognosis, but the adverse effects on the fetus can lead to premature birth, fetal distress and fetal death, etc., so that perinatal morbidity, mortality and premature delivery rate is high risk of pregnancy