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人支气管上皮细胞(BEC)在下呼吸道粘膜免疫和炎性应答中有着重要功能。本文主要研究BEC上表达的MHCⅡ类分子,当与葡萄球菌毒性休克综合征毒素1(TSST-1)结合后,能否进一步促进BEC的前炎性应答。
Human bronchial epithelial cells (BECs) play an important role in mucosal immunity and inflammatory response in the lower respiratory tract. This article focuses on whether MHC class II molecules expressed on BEC bind to staphylococcal toxic shock toxin 1 (TSST-1) and further promote the proinflammatory response of BEC.