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目的:探讨2型糖尿病(T2DM)合并心功能不全患者血清中BNP、Hcy以及Cys-c的水平变化情况和关系;方法:随机选取我院收治的单纯T2DM患者46例作为A组,另选取T2DM合并心功能不全早期患者50例作为B组,合并心功能不全晚期患者54例作为C组,对比3组患者间的BNP、Hcy以及Cys-c的水平及变化情况;结果:B、C两组的BNP、Hcy以及Cys-c水平明显高于A组患者,并且C组检测水平高于B组,P<0.05,具有统计学意义;结论:BNP、Hcy及Cys-c联合检验在诊断T2DM合并心功能不全时有着重要的意义,通过联合检验能够有效的评估出T2DM合并心功能不全的风险及预后。
Objective: To investigate the level changes and relationships combined with cardiac insufficiency the patient’s serum BNP, Hcy and Cys-c of type 2 diabetes mellitus (T2DM); Method: randomly admitted to our hospital alone T2DM 46 patients as Group A, the other selected T2DM Fifty patients with early cardiac dysfunction were selected as group B and 54 patients with advanced cardiac dysfunction as group C. The levels and changes of BNP, Hcy and Cys-c were compared between the three groups. Results: In groups B and C The levels of BNP, Hcy and Cys-c were significantly higher in group A than those in group A, and the detection level of group C was higher than that of group B (P <0.05) .Conclusion: The combination of BNP, Hcy and Cys- Cardiac insufficiency is of great significance, through the joint test can effectively assess the risk of T2DM with cardiac insufficiency and prognosis.