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目的:研究不同栽培居群红花的活血化瘀作用,探讨红花的种内变异,为药材的质量评价及优良栽培居群的选育提供依据。方法:测定血小板聚集抑制率、凝血酶原时间和部分凝血活酶时间,比较不同栽培居群红花的活血化瘀作用。结果:不同栽培居群红花活血化瘀药理作用存在非常显著差异(P<0.01),对血小板聚集的抑制作用,吉木萨尔居群>简阳居群>新乡居群和巍山居群(后两者间P>0.05);对凝血酶原和部分凝血活酶时间的延长作用,巍山居群>简阳居群>新乡居群和吉木萨尔居群(后两者间P>0.05)。结论:不同居群红花的活血化瘀作用因指标不同而不同,抑制血小板聚集吉木萨尔居群最优,延长凝血时间巍山居群最优
Objective: To study the effects of promoting blood circulation and removing blood stasis of cultivar safflower from different cultivation groups, and to discuss the intraspecific variation of safflower, so as to provide basis for quality evaluation of medicinal materials and breeding of excellent cultivation populations. Methods: The inhibition rate of platelet aggregation, prothrombin time, and partial thromboplastin time were measured. The effects of promoting blood circulation and removing blood stasis of safflower from different cultivation groups were compared. RESULTS: The pharmacological effects of safflower and blood circulation in different cultivated populations were significantly different (P<0.01), and the platelet aggregation was inhibited. Jimusar population> Jianyang population> Xinxiang population and Lushan population ( P>0.05 between the latter two; prolonged prothrombin and partial thromboplastin time, Lushan population> Jianyang population> Xinxiang population and Jimsar population (the latter two> P> 0 .05). Conclusion: The blood circulation and phlegm-removing effect of different populations of safflowers varies with different indicators. The inhibition of platelet aggregation Jimusar population is optimal, and the prolongation of coagulation time is the best for the population in Lushan Mountain.