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心律平属Ic类抗心律失常药,近年来用于治疗室上性及室性心律失常效果较好,一般认为它副作用少,广谱高效。但随着临床上广泛使用,证实其有很多的副反应。经查阅1998年以来各类医学文献报道心律平致心律失常160余例,其他不良反应8例。现将近年来心律平的不良反应综述如下。 1 心律平致心律失常反应抗心律失常药物有可能使原有心律失常加重或继发新的甚至更为严重的心律失常,这一现象称为抗心律失常药物的致心律失常作用。 1.1 心律平致心律失常的类型①束支传导阻滞:可表现为完全性左束支传导阻滞或完全性右束支传导阻滞;②Q-T间期延长;③房室传导阻滞(Ⅰ°Ⅱ°Ⅲ°);④窦性静止;⑤严重的窦性心动过缓;⑥持续性室性心动过速;⑦室颤;⑧窦房传导阻
Cardiac rhythm flat type Ic anti-arrhythmic drugs, in recent years for the treatment of supraventricular and ventricular arrhythmias better effect, generally considered less side effects, broad-spectrum efficient. But with the widespread use of clinically confirmed that it has a lot of side effects. After reviewing various types of medical literature since 1998, more than 160 cases of cardiac arrhythmia and 8 cases of other adverse reactions were reported. Now in recent years, the adverse reactions of heart rate Ping Ping are as follows. 1 arrhythmia caused by arrhythmia antiarrhythmic drugs may make the original arrhythmia or secondary to new and even more serious arrhythmia, a phenomenon called arrhythmic drugs antiarrhythmic effect. 1.1 type of arrhythmia caused by arrhythmia ① bundle branch block: can be expressed as complete left bundle branch block or right bundle branch block; ② Q-T interval prolongation; ③ atrioventricular block ( Ⅰ ° Ⅱ ° Ⅲ °); ④ sinus quiescence; ⑤ severe sinus bradycardia; ⑥ persistent ventricular tachycardia; ⑦ ventricular fibrillation;