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目的：探讨急性脑血管病患者血清Ｄ－二聚体水平与患者血栓前状态及血栓形成的关系。方法：采用Ｌａｔｅｘ法，分别对６４例脑梗塞，２９例脑出血，１４例高血压，１４例短暂性脑缺血发作（ＴＩＡ）及５０例正常人血清Ｄ－二聚体水平进行检测。结果：脑梗塞、脑出血、ＴＩＡ及高血压患者血清Ｄ－二聚体水平明显增高，其阳性率分别为７５％、７９％、２８％及２８％。与正常组比较均有显著性差异（Ｘ２检验，Ｐ＜０．０１）。结论：急性脑血管病患者均有不同程度的血栓形成倾向或血栓形成。提示检测急性脑血管病患者血清Ｄ－二聚体水平，对其病情观察、疗效考核和预后判断具有重要意义。
Objective: To investigate the relationship between serum D-dimer level and prethrombosis and thrombosis in patients with acute cerebrovascular disease. Methods: Latex method was used to detect the level of D-dimer in 64 cases of cerebral infarction, 29 cases of cerebral hemorrhage, 14 cases of hypertension, 14 cases of transient ischemic attack (TIA) and 50 cases of normal subjects. Results: The levels of serum D-dimer in patients with cerebral infarction, cerebral hemorrhage, TIA and hypertension were significantly increased, and the positive rates were 75%, 79%, 28% and 28% respectively. Compared with the normal group, there was significant difference (X2 test, P <0.01). Conclusion: Patients with acute cerebrovascular disease have different degrees of thrombophilia or thrombosis. Prompt detection of serum levels of D-dimer in patients with acute cerebrovascular disease, its condition observation, efficacy evaluation and prognosis of great significance.