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为了研究全胃切除、胃及幽门重建新术式对胃癌患者免疫功能的变化,测定了胃癌患者和非肿瘤手术病人术后05年,1年血液中IgA,IgC,IgM,CD4,CD8,IL-2,SIL-2R,INF-r水平。在新术式术中IgA,IgC,IgM,CD4,IL-2,INF-r水平明显高于传统术式组(P<001),与非肿瘤手术组相比差异不显著(P>005);CD8,SIL-2R水平在新术式中明显低于传统术式组(P<001),与非肿瘤手术组相比差异不显著(P>005)。提示:新术式患者术后免疫功能恢复快而持久,传统术式患者免疫功能恢复较慢且低下。
In order to study the effect of total gastrectomy, gastric and pyloric reconstruction on immune function in patients with gastric cancer, the levels of IgA, IgC, IgM, CD4, CD8 and IL in the blood of patients with gastric cancer and non-tumor patients after operation for one year and one year -2, SIL-2R, INF-r levels. The levels of IgA, IgC, IgM, CD4, IL-2 and INF-r in the new operation were significantly higher than those in the conventional operation group (P <001) . The levels of CD8 and SIL-2R in the new surgery group were significantly lower than those in the conventional surgery group (P <001), but not significantly different from those in the non-tumor surgery group (P> 005). It is suggested that the immune function in patients with neo-operative type recover quickly and persistently, and the immune function of patients in traditional surgical type recover slowly and lowly.