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目的对临床诊断为男性不育症患者进行细胞遗传学分析,探讨男性不育症与染色体之间的关系。方法常规方法制备外周血染色体标本,G显带。结果对男性不育症患者1285例进行染色体核型分析,共发现135例异常,异常率10.5%。结论染色体异常是造成男性不育的重要遗传因素,对精液检查异常者或男性性征发育不良者进行染色体检查,将有助于不育病因的诊断。
Objective To analyze the cytogenetics of clinically diagnosed male infertility and to explore the relationship between male infertility and chromosomes. Methods Peripheral blood chromosomal samples were prepared by routine methods and G banding. Results A total of 1285 cases of male infertility were analyzed by karyotype analysis. A total of 135 cases were found abnormal and the abnormality rate was 10.5%. Conclusion Chromosomal abnormalities are the important genetic factors that cause male infertility. Chromosomal examination of those with abnormal semen examination or male sexual dysplasia will be helpful for the diagnosis of infertility.