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目的分析大剂量甘露醇对肾功能的影响及防治措施。方法对急性脑出血患者住院治疗经过、各种并发症的产生及其转归进行回顾性分析,比较甘露醇的不同用法对肾功能的影响。结果本组132例中有46例使用小剂量甘露醇及速尿,6例因故未使用甘露醇,只有2例出现轻度肾功能异常,占4.35%;而有86例使用大剂量甘露醇,有30例出现不同程度的肾功能异常,占34.8%。结论大剂量甘露醇对急性脑卒中患者,尤其是60岁以上老年人,在其脱水降颅压的过程中,易致急性肾功能不全,严重影响疾病转归。而小剂量甘露醇则更为安全,且疗效相当,值得推广应用。
Objective To analyze the effect of high dose mannitol on renal function and its prevention and cure. Methods Acute cerebral hemorrhage in patients after hospitalization, the occurrence of various complications and their prognosis were retrospectively analyzed, comparing the different mannitol usage on renal function. Results In this group, 46 cases of low dose mannitol and furosemide were used in 46 cases, 6 cases were not used mannitol for some reason, only 2 cases showed mild renal dysfunction, accounting for 4.35%; while 86 cases were treated with high dose mannitol , There are 30 cases of varying degrees of renal dysfunction, accounting for 34.8%. Conclusion High doses of mannitol in patients with acute stroke, especially in the elderly over the age of 60, dehydration in the process of reducing intracranial pressure, easily lead to acute renal insufficiency, seriously affecting the outcome of the disease. The small dose of mannitol is more secure, and the effect is quite worthy of promotion and application.