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目的 研究类胰高血糖素肽-1(Glucagon-like peptide-1,GLP-1)在胎儿胃肠道中的分布情况。方法 应用免疫组织化学ABC法,对5例约23周左右胎儿胃肠道内GLP-1免疫活性细胞进行定位研究。结果 胎儿胃肠道中GLP-1免疫活性细胞密度最大是直肠,其次是结肠和回肠。结论 GLP-1免疫活性细胞主要分布在肠道远端。
Objective To study the distribution of Glucagon-like peptide-1 (GLP-1) in fetal gastrointestinal tract. Methods Immunohistochemical ABC method was used to study the localization of GLP-1 immunocompetent cells in fetal gastrointestinal tract in about 23 weeks. Results The highest density of GLP-1 immunocompetent cells in the fetal gastrointestinal tract was in the rectum, followed by the colon and ileum. Conclusion GLP-1 immunocompetent cells are mainly located in the distal gut.