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我院从1964年开始对中药墓头回抗癌作用初步进行实验研究,其结果为: 1.体外抑制实验;美兰试管法、伊红染色法、体外、体内细胞形态法均表明墓头回提取物对艾氏腹水癌瘤细胞有破坏作用。 2.墓头回对艾氏腹水癌有明显抑制作用,灌胃给药组平均生存时间第一次实验延长5.7天(53％)P值<0.001,第二次实验延长3.2天(21％)P值<0.01,腹水量及瘤细胞数较对照组明显减少,平均每只小鼠腹水量较对照组减少为4.38毫升,瘤细胞数减少为80192×10~6。 3.墓头回对艾氏实体型腹水癌有明显治疗作用,腹腔注射给药组第一次实验肿瘤抑制率达82％,P值<0.001,第二次实验肿瘤抑制率达78％,P值<0.001。皮下给药组肿瘤抑制率达64％P值<0.001。 4.墓头回局部注射可使局部肿瘤逐渐变硬、脱落、溃疡面修复治愈。
From 1964, our hospital began to conduct preliminary experiments on the anti-cancer effects of Chinese herbal medicine tombs. The results are as follows: 1. In vitro inhibition test; Meilan test tube, eosin staining, in vitro, and in vivo cell morphology methods all indicate tombs The extract has a destructive effect on Ehrlich ascites carcinoma cells. 2. Graves’ head back had a significant inhibitory effect on Ehrlich ascites carcinoma. The average survival time of gavage group was extended 5.7 days (53%) with a P value of <0.001, and the second experiment was extended by 3.2 days (21%). P value <0.01, the amount of ascites and the number of tumor cells were significantly reduced compared with the control group. The average amount of ascites in each mouse was reduced to 4.38 ml compared with the control group, and the number of tumor cells was reduced to 80192×10-6. 3. The tomb head had obvious curative effect on Ehrlich solid type ascites carcinoma. The inhibition rate of the first experiment tumor in the intraperitoneal injection group was 82%, P value was <0.001, and the second experiment tumor inhibition rate was 78%. Value < 0.001. In the subcutaneous group, the tumor inhibition rate was 64% with a P value < 0.001. 4. The local injection of the tomb head can gradually harden, shedding, and repair the ulcer surface.