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胃癌的病因至今尚未完全明了,真菌的致胃癌作用近年来受到重视。本文对病理确诊的18例胃白念珠菌病并发胃癌作了内镜和病理分析。结果明显:白念珠菌常见于溃疡型(61.1%)和浸润型(27.8%)的胃癌组织中,组织分型则以分化性腺癌(38.9%)和粘液腺癌(27.8%)为主。大部分白念珠菌位于组织的粘膜层(88.9%)。白念珠菌的致胃癌作用可能与其产生的Ⅱ级胺、黄曲霉毒素G1、B2等有关。白念珠菌在胃癌的发生、发展上可能起一定的作用。我们从活检粘膜病理方面作了分析。
The cause of gastric cancer has not yet been fully understood. The role of fungal gastric cancer has received attention in recent years. In this paper, endoscopic and pathological analysis of pathologically confirmed 18 cases of gastric candidiasis complicated with gastric cancer were performed. The results were clear: Candida albicans was common in ulcerated (61.1%) and infiltrating (27.8%) gastric cancer tissues, and histological type was differentiated adenocarcinoma (38.9%) and mucinous adenocarcinoma (27). .8%) mainly. Most Candida albicans are located in the mucosal layer of the tissue (88.9%). The gastric cancer-causing effect of Candida albicans may be related to the production of Class II amines, aflatoxins G1, B2, and the like. Candida albicans may play a role in the occurrence and development of gastric cancer. We analyzed the biopsy mucosal pathology.