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目的:探讨人工流产术后即时服用复方短效口服避孕药屈螺酮炔雌醇片的临床疗效及应用价值。方法:将260例符合人工流产终止妊娠的早孕妇女随机分成两组,观察组130例,术后立即服用屈螺酮炔雌醇片及益母草冲剂和抗生素。对照组130例,仅口服益母草冲剂及抗生素。观察两组人工流产术后阴道出血量及出血时间,月经恢复及再次妊娠情况,术后20天行超声检查观察子宫内膜厚度,术后并发症发生率。结果:两组阴道出血量少于等于月经量的分别占98.5%和90.0%(P<0.001);两组阴道出血在7天内干净者分别占96.2%和84.6%(P=0.003);两组37天内恢复月经分别占99.2%和79.1%(P<0.001);两组1个月内再次妊娠率分别为0和8.3%(P=0.026);两组术后20天子宫内膜厚度≥1.0 cm分别占98.5%和90.8%(P=0.011);观察组术后并发症发生率明显低于对照组(P=0.03)。结论:与仅服用益母草冲剂和抗生素相比,加服屈螺酮炔雌醇片能使人工流产术后患者的月经恢复快、周期规律、阴道出血量少、出血时间短,能促进子宫内膜早期修复,减少术后并发症,避孕效果好。
Objective: To investigate the clinical curative effect and application value of instant administration of compound short-acting oral contraceptive dapsone ethinyl estradiol tablets after induced abortion. Methods: Two hundred and seventy pregnant women with terminating pregnancy induced abortion were randomly divided into two groups. 130 cases in the observation group were given drospirenone ethinyl estradiol tablets and motherwort granules and antibiotics immediately after operation. Control group of 130 cases, only oral motherwort granules and antibiotics. The vaginal bleeding volume, bleeding time, menstruation recovery and pregnancy again after operation were observed. The thickness of endometrium and the incidence of postoperative complications were observed 20 days after operation. Results: The vaginal bleeding amount was less than or equal to 98.5% and 90.0% respectively (P <0.001) in two groups; 96.2% and 84.6% (P = 0.003) respectively in 7 days in both groups; The recovery rate of menstruation in 37 days were 99.2% and 79.1% respectively (P <0.001). The pregnancy rates in two groups were 0 and 8.3% within 1 month respectively (P = 0.026). The thickness of endometrium was ≥1.0 cm respectively accounted for 98.5% and 90.8% (P = 0.011). The incidence of postoperative complications in the observation group was significantly lower than that in the control group (P = 0.03). CONCLUSIONS: Compared with taking motherwort granules and antibiotics alone, adding drospirenone ethinyl estradiol tablets can make the menstrual recovery faster, the periodic pattern, the less vaginal bleeding, the shorter bleeding time and the promotion of endometrium Early repair, reduce postoperative complications, good contraception.