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目的 探讨米索前列醇在宫腔镜检查术中对宫颈软化的效果。方法 60例官腔镜检查患者随机分为两组,30例(用药组)术前2～18小时阴道后穹隆放置米索前列醇200μg;30例(对照组)未放置任何药物。观察术中的宫颈软化情况、两组扩宫率、扩张宫颈所需时间、患者疼痛情况及用药组副反应发生情况。结果 用药组较对照组扩宫率下降,扩张宫颈更轻松,扩张宫颈所需时间明显缩短,差异有极显著性意义(P<0.01);感觉疼痛的机率减少,疼痛程度明显减轻,差异有极显著性意义(P<0.01);用药组无明显副反应发生。结论 术前阴道后穹隆放置米索前列醇以软化宫颈是一项安全、简单、有效的方法。
Objective To investigate the effect of misoprostol on cervix softening during hysteroscopy. Methods Sixty patients undergoing endoscopic examination were randomly divided into two groups. 30 patients (medication group) were given misoprostol 200μg intravaginally for 2 ~ 18 hours before operation. No drug was administered to 30 patients (control group). Observation of intraoperative cervical softening, two groups of expansion rate, the time required to expand the cervix, the patient’s pain and side effects of medication group. Results Compared with the control group, the dilatation rate of the cervix was decreased, the dilatation of the cervix was more relaxed and the dilatation of the cervix was shorter. The difference was significant (P <0.01). The chances of feeling pain were reduced and the degree of pain was relieved Significant significance (P <0.01); medication group no obvious side effects. Conclusion Preoperative vaginal posterior fornix misoprostol to soften the cervix is a safe, simple and effective method.