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在泰国对9-菲甲醇(WR 33063)和9-喹啉甲醇(WR 30090)两种新抗疟药治疗恶性疟的疗效进行了观察,并与奎宁作了比较。 214例治疗对象为确诊的恶性疟患者,血检每立方毫米血内含有恶性疟原虫1,000～100,000个,并有高热及其他明显的临床症状,但无夹杂症及间日疟的感染。 WR 33063和WR 30090均用胶囊盛装,WR 33063胶囊每颗含量为200毫克,每8小时服600毫克,连服6天,共服18次,总剂量为10.8克。WR 30090胶囊每颗含量
The efficacy of two new antimalarial drugs for 9-meflumetol (WR 33063) and 9-quinolinemethanol (WR 30090) for the treatment of P. falciparum in Thailand was observed and compared with quinine. 214 patients were diagnosed with falciparum malaria patients, blood tests per cubic millimeter of blood contains Plasmodium falciparum 1,000 to 100,000, and have high fever and other obvious clinical symptoms, but no inclusions and vivax malaria infection. WR 33063 and WR 30090 are both in capsules. The WR 33063 capsule contains 200 mg per capsule and 600 mg every 8 hours for a total of 18 doses for a total of 18 doses for a total of 10.8 grams. WR 30090 capsules each content