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61例活动性肢端肥大症(肢大)患者中,并发阻塞性睡眠呼吸暂停26例(42.6％)。肢大有睡眠呼吸暂停组21例与无睡眠呼吸暂停组14例的多导睡眠图检查结果及血生长激素(GH)基础值和葡萄糖抑制峰值进行了比较,两组身高、Ⅲ+Ⅳ期深睡、最长和平均呼吸暂停时间、呼吸紊乱指数和最低SaO_2百分率改变等差异有显著性(P<0.05～0.001);前者的睡眠时打鼾、常被憋醒和白天嗜睡等症状均较后者明显;血GH基础值和葡萄糖抑制GH峰值间则差异无显著性。
Among the 61 patients with active acromegaly (limbs), 26 patients (42.6%) had obstructive sleep apnea. The results of polysomnography and baseline values of GH and glucose suppression in 21 patients with sleep apnea and 14 patients without sleep apnea were compared. The height, stage III + IV Sleep, the longest and average apnea time, respiratory disorder index and the lowest percentage of SaO_2 were significantly different (P <0.05 ~ 0.001); the former snoring sleep, often wake up and daytime sleepiness and other symptoms than the latter Obviously, there was no significant difference between the basal value of blood GH and the peak of glucose inhibition GH.