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目的：对比肌内注射（肌注）低张药物、口服阴性对比剂及肌注低张药物结合口服阴性对比剂3种方法进行肠道准备后对正常十二指肠壶腹及周围解剖结构显示的差异。方法将健康体检者60例随机分为3组各20例，分别采用肌注消旋山茛菪碱（654－2肌注组）、饮温开水（饮水组）和肌注654－2注射液结合饮温开水（654－2肌注＋饮水组）进行肠道准备。3组体检者分别行肠道准备后壶腹部CT扫描。结果3种肠道准备后CT扫描图像对十二指肠肠腔扩张度，胆总管下段、壶腹部、十二指肠乳头及十二指肠黏膜显示差异有统计学意义（P＜0．05），654－2肌注＋饮水组十二指肠、壶腹部解剖结构的显示结果最佳。结论肌注低张药物结合口服阴性对比剂肠道准备后CT扫描有利于正常十二指肠、壶腹部周围解剖结构的显示，为最优肠道准备方法。“,”Objective To observe the differences of the normal duodenal ampulla and surrounding anatomical struc -tures display by intramuscular injection hypotonic drugs ,negative oral contrast agent ,intramuscular injection of hypotonic drugs with negative oral contrast agent three kinds of methods of bowel preparation .Methods 60 cases of healthy people were ran-domly divided into A group,B group and C group,each of 20 people,bowel preparation were given with intremuscular injected 654-2 injection ,drunk warm water ,and injecting 654-2 injection combined with drunk warm water respectively .3 groups health-y people were performed CT examination after bowel preparation .Results 3 kinds of bowel preparation for CT scan images of the duodenum lumen expansion,common bile duct,ampulla,duodenal mucosa and duodenal showed statistically significant differences(P<0.05).Intramuscular 654-2 combined water duodenum,ampulla anatomy showed the best results .Conclusion The best bowel preparation of injected 654-2,drunk warm water,before CT examination are increasing showed of normal duo -denal papilla anatomy in CT imaging.