The northeastern China is a sensitive region of climate change, whose detailed trend of climate changes is highly interesting. In this study, this kind of variation trend was analyzed. Potential evapotranspiration (PE) and moisture index (MI) were modeled by using Thornthwaite scheme based on the observation data of 1961-2004 from 94 meteorological stations. To describe the climate fluctuation in the northeastern China in 1961-2000, the linear regression method was used to analyze the variation trends of mean annual temperature, mean annual precipitation, PE and MI. Mann-Kendall method was used to test the significant difference. The results show a general increasing tendency in mean annual temperature, mean annual precipitation, PE and MI. However increasing tendency was more significant in mean annual temperature and PE than in mean annual precipitation and MI. Analysis of seasonal climate variation indicates that there showed positive trends in winter and in spring, while the positive trend was more significant in winter than in spring. Furthermore, the relations between climate changes and geographical factors were analyzed, the results show that both climate factors and their interannual variability were correlated to latitude, longitude and altitude,suggesting that latitude is the most climate factor affecting climate changes, followed by altitude and longitude.