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术中自体血回收(intraoperative cell salvage,IOCS)一直以来由于白细胞污染、羊水栓塞的风险、胎儿红细胞引起的母体同种异体免疫反应等顾虑在产科中的应用受到一定的限制,近年来随着白细胞滤器(leucocyte depletion filters,LDF)的应用,其在产科得到了很好的开展。LDF为膜状结构,可滤除产科回收血中的杂质及污染物,如:胎儿鳞状上皮细胞、组织因子、甲胎蛋白、板层小体等羊水成分以及白细胞、胎儿红细胞、细菌等。但同时亦存在相关并发症,应防止加压,谨慎使用。临床上应对LDF应用于产科的安全性进行深入的研究。
Intraoperative cell salvage (IOCS) has long been used in obstetrics because of leukocyte contamination, risk of amniotic fluid embolism, maternal allogeneic immune response caused by fetal red blood cells, etc. In recent years, as white blood cells The application of leucocyte depletion filters (LDFs) has been well developed in obstetrics. LDF is a membranous structure that can filter obstetric recovery of blood impurities and contaminants such as fetal squamous cells, tissue factor, alpha-fetoprotein, lamellar body and other amniotic fluid components and white blood cells, fetal red blood cells, bacteria and so on. But at the same time there are also related complications, should prevent the use of pressure, caution. Clinically, LDF should be applied to obstetric safety in-depth study.