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目的:探讨中性粒细胞在深Ⅱ度烧伤创面早期进行性损伤中的作用。方法:分析360例烧伤患者的血常规检查报告中性粒细胞的变化,观察烧伤深Ⅱ度创面的愈合时间。结果:入院时中性粒细胞均高于正常,很快降至正常的创面愈合快,下降慢的深Ⅱ度创面愈合时间延长。结论:中性粒细胞导致的创面损伤可能烧伤后即发生,入院后应使用抗氧化剂及蛋白酶抑制剂。
Objective: To investigate the role of neutrophils in the early progressive injury of deep second degree burn wounds. Methods: The changes of polymorphonuclear neutrophils in 360 cases of burn patients were analyzed. The healing time of deep second degree burn wounds was observed. Results: Neonatal neutrophils were higher than normal at admission, the wound healing quickly dropped to normal, and the slowing deep second-degree wound healing time was prolonged. CONCLUSIONS: Neonatal granulocyte-induced wound injury may occur immediately after burn injury. Antioxidants and protease inhibitors should be used after admission.