男性生殖系炎症一直被认为是造成男性不育的原因之一。近年来,随着男性生殖医学的发展,因不育而就诊的男性患者日渐增多,这类疾患也显得更为多见。然而,男性生殖系统慢性炎症究竟能否影响正常生育至今并不十分清楚。现将近年有关这方面问题的研究作一些综合讨论。男性生殖系特发性感染如附睾输精管结核,急性腮腺炎并发的睾丸炎以及淋菌性附睾炎等都可通过直接损坏睾丸生精组织或造成精子输送管道梗阻而影响生育功能。但是在不育患者中,这类特发性感染只是很少数,而绝大多数炎症属于慢性非特异性,特别是所谓亚临床型炎症。这种患者一般没有任何临床表现,仅在因不育症就诊时,检查 Male genital inflammation has long been considered one of the causes of male infertility. In recent years, with the development of male reproductive medicine, the number of male patients treated for infertility has been on the rise. Such diseases are also more common. However, it remains unclear whether chronic inflammation of the male reproductive system affects normal fertility. In recent years, we have made some comprehensive discussions on the research on this issue. Male genital system idiopathic infections such as epididymis vas deferens tuberculosis, acute parotitis complicated with orchitis and gonococcal epididymitis, etc. can be directly damaged by testicular spermatogenesis or sperm duct obstruction and affect fertility. However, in infertility patients, only a very small number of these idiopathic infections, and the vast majority of inflammation are chronic non-specific, especially the so-called subclinical inflammation. Such patients generally do not have any clinical manifestations, only when infertility treatment, check