军团菌感染的主要诊断方法包括分离培养法、尿抗原检测法、免疫学方法和核酸扩增法,每种检测方法各有利弊。由于军团菌分型复杂以及检测方法的局限性,军团菌感染处于被低估状态。军团菌感染常表现为重症,应积极进行多种方法检测以早期诊断、早期目标治疗,进而改善患者预后、降低病死率。 The main diagnostic methods for Legionella infection include isolation and culture methods, urine antigen detection methods, immunological methods and nucleic acid amplification methods, each with its own advantages and disadvantages. Due to the complex typing of Legionella and the limitations of detection methods, Legionella infection is undervalued. Legionella infection often presents as severe, should be actively testing a variety of methods to early diagnosis and early target treatment, thereby improving patient prognosis and reduce mortality.