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目的:研究鼻息肉组织中炎性细胞的病理意义。方法:对 10 例正常鼻粘膜和24 例鼻息肉组织行免疫组化及 M G G 染色以观察嗜酸性粒细胞、单核细胞、巨噬细胞在组织中的分布程度。结果:鼻息肉组织中嗜酸性粒细胞、 C D68 阳性巨噬细胞和单核细胞显著增加。结论:鼻息肉的发生与炎性细胞的浸润、活化密切相关,药物治疗应是鼻息肉病治疗中的一个重要方面。
Objective: To study the pathological significance of inflammatory cells in nasal polyps. Methods: Immunohistochemistry and M G G staining of 10 normal nasal mucosa and 24 cases of nasal polyps were performed to observe the distribution of eosinophils, monocytes and macrophages in the tissues. Results: Eosinophils, C-D68-positive macrophages and monocytes were significantly increased in nasal polyps. Conclusion: The occurrence of nasal polyps is closely related to the infiltration and activation of inflammatory cells. Drug treatment should be an important aspect of the treatment of nasal polyposis.