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目的 :探究阿替普酶联合丁苯肽注射液对超早期缺血性卒中患者神经功能缺损的影响分析。方法 :选取我院2013年1月~2014年1月收治的65例超早期缺血性卒中患者,随机分为观察组和对照组,对照组患者40例,使用阿替普酶对患者进行治疗;观察组25例,使用阿替普酶联合丁苯酞注射液进行治疗,观察两组治疗效果。结果 :治疗前后观察组Ho-1和APN变化较对照组有明显差异;治疗后观察组患者7天ADL和NIHSS与对照组无明显差异;30天观察组ADL和NIHSS优于对照组,差异具有统计学意义;3个月观察组ADL和NIHSS优于对照组,差异具有统计学意义。结论 :观察组患者将阿替普酶和丁苯酞注射液联合使用,治疗效果更为显著,有助于改善超早期缺血性卒中患者的神经功能缺损。
Objective: To investigate the effect of alteplase and buprenorphine on neurological deficits in patients with early ischemic stroke. Methods: Sixty-five patients with ultra-early ischemic stroke admitted from January 2013 to January 2014 in our hospital were randomly divided into observation group and control group, and 40 patients in control group were treated with alteplase ; Observation group of 25 cases, the use of alteplase combined with butylphthalide injection for treatment, the two groups were observed. Results: The changes of Ho-1 and APN in the observation group before and after treatment were significantly different from those in the control group. After treatment, the ADL and NIHSS in the observation group had no significant difference with the control group on the 7th day; the ADL and NIHSS in the 30-day observation group were superior to the control group, Statistical significance; 3-month observation group ADL and NIHSS better than the control group, the difference was statistically significant. Conclusions: The combination of alteplase and butylphthalide in the observation group is more effective in treating neurological deficits in patients with early ischemic stroke.