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糖化血红蛋白(英文缩写GHb或HbA1C)是葡萄糖与血红蛋白结合形成的产物,它的形成是非酶促的单向进行的,故不可逆转,只能自然凋亡。所以糖化血红蛋白的浓度会随着血糖浓度的升高而升高[1]。又因为测定糖化血红蛋白不受临时血糖浓度波动的影响,所以其结果可有效地反映患者过去一段时间的平均血糖水平,这样可以很好的反应糖尿病患者在一段时间内的血糖控制情况。但是对于糖尿病诊断,测定糖化血红蛋白的实际用处不是很大。糖化血红蛋白是糖尿病的筛选、血糖控制、疗效考核的有效检测指标,被称为金指标,其检测结果在临床上的应用有着重要的意义。本文主要目的就是探讨、分析糖化血红蛋白的监测结果在临床的应用以及意义。
Glycosylated hemoglobin (abbreviation GHb or HbA1C) is a product of the combination of glucose and hemoglobin, its formation is non-enzymatic one-way, it is irreversible, only natural apoptosis. Therefore, the concentration of glycosylated hemoglobin will increase with the increase of blood glucose concentration [1]. And because the determination of HbA1c is not affected by the temporary fluctuations in blood glucose concentration, the results can effectively reflect the average blood glucose level of patients over the past period, which can well reflect the glycemic control of diabetic patients over a period of time. But for the diagnosis of diabetes, the actual use of glycosylated hemoglobin is not significant. Glycosylated hemoglobin is an effective measure of diabetes screening, glycemic control, and curative effect evaluation, which is called the gold index. The test results are of great significance in clinical application. The main purpose of this paper is to explore and analyze the clinical application and significance of the monitoring results of glycosylated hemoglobin.