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目的 :比较艾司洛尔复合硝普钠与单纯硝普钠降压效果。方法 :2 8例病人随机分为两组 ,观察并比较两组降压时血液动力学变化。结果 :艾司洛尔能明显加快硝普钠起效速率 ,硝普钠用量明显减少 ,并能抑制单纯硝普钠降压时反射性心率增快 ;停止降压后血压平稳上升 ,心率收缩压乘积值下降 ,与单纯硝普钠组比较有显著差异。结论 :艾司洛尔复合硝普钠降压有明显的协同作用 ,无反跳现象
Objective: To compare the antihypertensive effect of esmolol sodium nitroprusside and sodium nitroprusside. Methods: Twenty-eight patients were randomly divided into two groups. The hemodynamic changes of the two groups were observed and compared. RESULTS: Esmolol significantly accelerated the onset of sodium nitroprusside, decreased the dosage of sodium nitroprusside, and inhibited the rapid increase of reflexive heart rate when nitric sodium was depressurized. The blood pressure increased steadily after stopping decompression, and systolic blood pressure Product value decreased, compared with simple sodium nitroprusside group were significantly different. Conclusion: Esmolol combined with sodium nitroprusside has obvious synergistic effect on blood pressure lowering without rebound phenomenon