L型麻风患者不能控制其疾病发展,可能是因为有巨噬细胞的功能缺陷。这可由麻风菌引起,也可能是因为缺少依赖T淋巴细胞的巨噬细胞刺激。非特异性防御机能缺陷在麻风中起作用的假说被越来越多的人所接受。这一机能部份负责宿主对杆菌的抵抗。巨噬细胞不能向免疫系统呈递麻风抗原的设想,促使人们用BCG和麻风菌素为麻风进行 L-type leprosy patients can not control the development of their disease, it may be due to the functional defects of macrophages. This may be caused by leprosy or may be due to the lack of T-lymphocyte-dependent macrophage stimulation. The hypothesis that nonspecific defense dysfunction plays a role in leprosy is accepted by more and more people. This function is partly responsible for host resistance to Bacillus. The inability of macrophages to deliver leprosy antigens to the immune system has prompted people to leprosy with BCG and lepirudin