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目的观察醒脑静注射液佐治急性缺血性脑卒中的疗效及安全性。方法将166例患者随机分为两组,对照组81例采用内科常规方法治疗,治疗组85例在常规方法治疗的基础上加用醒脑静注射液静滴,两组疗程均为14d;比较两组治疗前后中医证候积分、临床疗效、神经功能缺损评分及生活能力状态。结果治疗组中医证候疗效优于对照组,其中医证候总积分改善亦优于对照组;两组神经功能缺损评分差异有显著性。出院后经3个月随访,治疗组生活能力状态优于对照组。结论急性缺血性脑卒中在内科常规治疗的基础上佐以醒脑静注射液能明显改善患者的中医证候和神经功能缺损,提高临床疗效和生活能力。
Objective To observe the efficacy and safety of Xingnaojing injection in adjuvant acute ischemic stroke. Methods One hundred and sixty-six patients were randomly divided into two groups. The control group of 81 cases were treated by conventional medical method. 85 cases in the treatment group received intravenous xujingjing injection on the basis of conventional treatment. The treatment duration was 14 days. Before and after treatment, TCM syndrome score, clinical curative effect, neurological deficit score and life status. Results The therapeutic effect of TCM syndrome in treatment group was better than that in control group, and the total score of TCM syndrome improved better than that in control group. There was significant difference between the two groups in neurological deficit score. After 3 months of follow-up after discharge, the viability of the treatment group was better than that of the control group. Conclusion Acute ischemic stroke in the conventional medical treatment based on the combination of Xingnaojing injection can significantly improve the patient’s syndromes and neurological deficits, improve clinical efficacy and life skills.