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目的观察红花液联合低分子肝素(LMWH)治疗不稳定型心绞痛的疗效及安全性。方法将103例不稳定性型心绞痛患者随机分为3组,3组均给予常规治疗,红花液组35例20m l静滴,每日1次,疗程14d,(LMWH)组34例加用低分子肝素(LMEH)4100 IU皮下注射,1次/12h,共用7d,红花液加LMWH组(34例),同时加用红花液、LMWH,疗程14d。14d后分别观察3组治疗前后的心绞痛发作率、心电图和血清总胆固醇(TC)、低密度脂蛋白(LDL)等。结果红花液联合低分子肝素能有效缓解症状,改善心电图疗效,心肌耗氧量明显下降(P<0.05)结论红花液联合低分子肝素治疗不稳定型心绞痛安全、有效。
Objective To observe the efficacy and safety of safflower combined with low molecular weight heparin (LMWH) in the treatment of unstable angina pectoris. Methods 103 patients with unstable angina pectoris were randomly divided into three groups, three groups were given conventional treatment, 35 cases of safflower liquid group 20ml intravenous infusion once a day for 14 days, (LMWH) group, 34 cases were added Low molecular weight heparin (LMEH) 4100 IU subcutaneous injection, 1 / 12h, shared 7d, safflower plus LMWH group (34 cases), plus safflower solution, LMWH, treatment 14d. After 14 days, the incidences of angina pectoris, electrocardiogram, serum total cholesterol (TC) and low density lipoprotein (LDL) were observed before and after treatment. Results Safflower combined with low molecular weight heparin can effectively relieve the symptoms and improve the curative effect of electrocardiogram and myocardial oxygen consumption decreased obviously (P <0.05). Conclusion Safflower combined with low molecular weight heparin is safe and effective in the treatment of unstable angina pectoris.