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采用放射免疫方法测定了正常人、急性心肌梗塞和不稳定型心绞痛患者血浆β内啡肽、强啡肽和精氨酸加压素（ＡＶＰ）的浓度。结果：血浆β内啡肽、强啡肽和ＡＶＰ浓度在ＡＭＩ、不稳定型心绞痛患者较正常人明显增高（Ｐ＜０．００１，Ｐ＜０．０１），而在ＡＭＩ组与不稳定型心绞痛组３种激素浓度均无显著性差异（Ｐ均＞０．０５）。ＡＭＩ组９例有严重并发症者与１３例无并发症者相比，有并发症者３种激素均显著高于无并发症者（Ｐ均＜０．０５）。提示：缺血性疼痛是一个强的应激原，导致这些激素释放增加，另外，内阿片肽和ＡＶＰ在缺血性疼痛刺激下平行升高可能是使机体在应激状态时保持内环境的相对稳定，是机体在长期进化过程中的适应代偿机制之一
The concentrations of plasma beta endorphin, dynorphin and arginine vasopressin (AVP) were measured by radioimmunoassay in normal subjects, patients with acute myocardial infarction and patients with unstable angina pectoris. Results: The levels of plasma beta endorphin, dynorphin and AVP in patients with AMI and unstable angina pectoris were significantly higher than those in normal controls (P <0.001, P <0.01), but not in AMI patients with unstable angina pectoris There was no significant difference in the concentrations of three hormones (P> 0.05). There were 9 cases of severe complications in AMI group compared with 13 cases without complications. All three hormones with complications were significantly higher than those without complications (all P <0.05). Tip: Ischemic pain is a strong stressor leading to increased release of these hormones. In addition, the parallel elevation of endogenous opioid peptides and AVP following ischemic pain stimulation may be responsible for maintaining the body’s internal environment during stress Relatively stable, is one of the body’s compensatory mechanisms in the long-term evolutionary process