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我们将粒度40~60μm铜粉(99.5%)、氯化钠(99.8%)各50mg与栓堵剂MPU0.06ml混匀后注入兔输精管并保持管腔通畅;该铜栓体外释放测定1.935μg/d,其铜离子浓度可使离体精子在3~6小时达完全制动。经对25只家兔注射后30、90、180、270、360天观察,输精管腔内铜栓通道通畅率分别为100%、44%、32%、12%、4%,活精子率分别为15.3%、10.5%、9.7%、0%、0%,合笼试验雌兔均未受孕。提示:在通道堵塞前铜栓释放的铜离子可使精子活力、活率明显下降,死精子及断头率明显上升,达节育水平;铜栓通道虽未能永久保持却有效的缓解和避免了术后附睾淤积的发生
We will be 40 ~ 60μm particle size of copper powder (99.5%), sodium chloride (99.8%) 50mg and plugging agent MPU0.06ml mixed into the rabbit vas deferens and maintain lumen patency; the copper bolt in vitro release Determination of 1.935μg / d, the copper ion concentration in vitro sperm in 3 to 6 hours to reach full braking. After 30, 90, 180, 270, 360 days after injection, the patency rates of intraluminal copper plug were 100%, 44%, 32%, 12% and 4%, respectively 15.3%, 10.5%, 9.7%, 0%, 0% TIP: The release of copper ions in the copper plug before the channel blockages can significantly reduce the viability and viability of sperm, increase the number of dead sperm and the decapitation, up to the level of birth control. Although the copper channel is not permanently maintained, it is effectively alleviated and avoided Postoperative epididymal deposition occurred