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目的探讨Graver’s病131碘治疗前后彩超血流动力学及甲状腺激素的变化。方法对124例Graver’s病131碘治疗前后进行二维及彩色多普勒血流显像(CDFI)及血清甲状腺激素分析,并与25例正常人做对照。结果正常组甲状腺内血流正常,Graver’s病组腺体血流明显增加,Graver’s病组治疗前后甲状腺体积、甲状腺上动脉血流速度、血清甲状腺激素水平差异均有显著性(P<0.01或P<0.05)。结论对Graver’s病的诊断以及131碘治疗效果的评估,除了临床表现、实验室检查外,彩色多普勒超声检查是一种快速、简便的观察手段,有着十分重要的临床应用价值。
Objective To investigate the changes of color Doppler flow dynamics and thyroid hormones before and after Graver’s disease 131 iodine treatment. Methods Two-dimensional and color Doppler flow imaging (CDFI) and serum thyroid hormones were analyzed before and after 124 Graves’ disease 131 iodine treatment, and compared with 25 healthy controls. Results The flow of thyroid gland in normal group was normal, the glandular blood flow in Graver’s disease group was significantly increased, the volume of thyroid gland, the velocity of thyroid artery blood flow and serum thyroid hormone in Graver’s disease group were significantly different before and after treatment (P <0.01 or P < 0.05). Conclusion The diagnosis of Graver ’s disease and the evaluation of the effect of 131I treatment, in addition to clinical manifestations and laboratory tests, color Doppler ultrasonography is a rapid and simple observation method and has very important clinical value.