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肾移植术后功能延迟恢复(DGF)的因素甚多,国外报道其发生率高达10%~60%。本文介绍我院15年来的尸体肾移植情况:DGF发生率仅为5.74/.远低于国外报道。其原因分别为急性肾小管坏死(ATN),占77.59%;急性排异反应,占15.52%;泌尿系并发症,占5.17%;急性CsA肾毒性,占1.72%。其预防方法包括:选择年轻健康供者;缩短热、温缺血时间;保存液中引进钙离子拮抗剂;木中避免缩血管药物的应用及避免术后泌尿系并发症的发生;经济条件允许者预防性应用单、多克隆抗体;警惕急性CsA肾毒性。
Delayed functional recovery after kidney transplantation (DGF) a lot of factors, the incidence of foreign reports up to 10% to 60%. This article describes the 15-year cadaveric kidney transplant in our hospital: the incidence of DGF was only 5.74 /. Far below foreign reports. The reasons were acute tubular necrosis (ATN), accounting for 77.59%; acute rejection, accounting for 15.52%; urological complications, accounting for 5.17%; acute CsA nephrotoxicity, accounting for 1.72% . The prevention methods include: selecting young and healthy donors; shortening the warm and warm ischemic time; preservative solution introduction of calcium antagonists; wood to avoid the application of vasoconstrictor drugs and to avoid postoperative urological complications; economic conditions allow Preventive use of single and polyclonal antibodies; vigilant against acute CsA nephrotoxicity.