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用多种单克隆抗体(mAbs)检测了110例经形态学和细胞化学诊断的成人急性髓细胞白血病(AML)的免疫表型。其中男63例,女47例;平均年龄45岁(14～82岁),M_03例,M_119例,M_227例,M_317例,M_431例,M_513例。 通过直接免疫荧光技术和荧光双标记(异氰酸荧光素和藻红蛋白)染色,用流式细胞仪检测白血病原始细胞,当>20％的原始细胞表达淋巴细胞系相关抗原时视为Ly阳性,据此可将受检患者分为二组:56/110(51％)的患者仅表达髓系抗原(My/AML);54/110
The immunophenotypes of 110 adult patients with acute myeloid leukemia (AML) diagnosed by morphology and cytochemistry were examined using a variety of monoclonal antibodies (mAbs). There were 63 males and 47 females with a mean age of 45 years (range 14-82 years). There were M_03 cases, M_119 cases, M_227 cases, M_317 cases, M_431 cases and M_513 cases. Leukemia blasts were detected by direct immunofluorescence and fluorescent double labeling (fluorescein isocyanurate and phycoerythrin), and Ly positive when> 20% of blast cells expressed lymphocyte lineage-associated antigens , According to which patients can be divided into two groups: 56/110 (51%) only express myeloid antigen (My / AML); 54/110