论文部分内容阅读
作者为了深入了解銻剂在治疗血吸虫病时,对机体组织损害的情况、对成虫作用的机制和药物对组织内虫卵的影响等问题,利用小白鼠278只,家兔76只,分为6组进行了实验研究。研究结果说明:(1)銻剂治疗能引起肝细胞变性,门静脉区白血球浸润和肝组织结构紊乱、坏死出血等变化。心、肾、肺等组织有轻度的变性;(2)銻剂治疗中动物中毒死亡的原因,可能是由于肝组织广泛地被破坏和机能遭受严重损坏的结果;(3)内臟组织中,锑的含量以肝臟为最高,治疗完毕后8周各
In order to further understand the antimony agent in the treatment of schistosomiasis, the damage to the body tissue, the mechanism of action of adults and drugs on the impact of tissue eggs and other issues, the use of mice 278, 76 rabbits were divided into 6 Group conducted an experimental study. The results show that: (1) Antimony agent treatment can cause degeneration of liver cells, portal vein white blood cell infiltration and liver tissue disorders, necrosis and other changes. Heart, kidney, lungs and other organizations have mild degeneration; (2) antimony agent treatment of animal deaths caused by poisoning may be due to extensive destruction of liver tissue and function suffered serious damage results; (3) visceral tissue , The content of antimony in the liver as the highest, 8 weeks after treatment