论文部分内容阅读
目的探索发病村村民与周围自然村村民的心肌酶在本病流行期和非流行期是否存在差异,为深入开展具有针对性的病因研究提供线索。方法选取发病村村民24人和3个对照村每村30人作为研究对象,在流行期和非流行期分别采集研究人群的血清作心肌酶、肝、肾功等检测。结果发病村和对照村人群的4个心肌酶指标在各次检测中异常率均较高,依次是CK-MB、CK、HBDH、LDH。发病村异常率高于对照村;CK-MB/CK均大于5%;CK-MB最高值为上限值5倍,CK为4倍,HBDH为2.36倍,LDH为1.5倍;发病村人群非流行期LDH,HBDH较流行期明显下降。结论发病村村民和同在一山系的对照村村民的4种心肌酶指标异常率在流行期和非流行期均较高,提示该地区(山系)自然环境中可能存在某些致心肌酶增高的危险因素。
Objective To explore whether there is a difference in myocardial enzyme between the villagers in the affected villages and villagers in the surrounding natural villages during the epidemic and non-epidemic periods of this disease, so as to provide clues for further research on the etiological research. Methods Twenty-four villagers in the diseased village and 30 villagers in each of the three control villages were enrolled in this study. The sera of the study population were collected for the detection of myocardial enzymes, liver and kidney function during the epidemic and non-epidemic periods respectively. Results The incidences of abnormalities of four myocardial enzymes in the affected and control villages were higher in all tests, followed by CK-MB, CK, HBDH and LDH. The incidence of abnormalities in the village was higher than that in the control village; the CK-MB / CK was more than 5%; the highest CK-MB was 5 times the upper limit, CK was 4 times, HBDH was 2.36 times, LDH was 1.5 times; Prevalence of LDH, HBDH decreased significantly over the epidemic. Conclusions The abnormal rates of four kinds of myocardial enzymes in villagers of the affected villages and villagers in the same mountainous area are higher in both prevalence and non-epidemic periods, suggesting that there may be some elevated myocardial enzymes in the natural environment of this area Risk factors.