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A novel Schiff base complex with π-conjugated system, [Ni(L1)2(py)2] 1 (L1 = (E)-N’-(2,4-dichlorobenzylidene)-2-oxidobenzohydraizide), was synthesized and characterized by elemental analysis and single-crystal X-ray determination. Complex 1 crystallizes in the monoclinic system, space group P21/n with a = 12.8286(10), b = 16.3573(13), c = 19.0206(14) , β = 108.2920(10)o, V = 3789.6(5) 3, Z = 4, Mr = 833.17, Dc = 1.460 g/cm3, μ = 0.843 mm-1, F(000) = 1704, the final R = 0.0537 and wR = 0.0640 for 3836 observed reflections with I > 2σ(I). In the molecular structure of 1, the NiII atoms are six-coordinated by two N and two O atoms from two Schiff base ligands (L1) and two N atoms from two pyridine solvent molecules to form a distorted octahedral geometry. The cytotoxic activities of complex 1 have been experimentally studied against a human HeLa cell in vitro.
A novel Schiff base complex with π-conjugated system, [Ni (L1) 2 (py) 2] 1 (L1 = (E) -N’- (2,4- dichlorobenzylidene) -2-oxidobenzohydraizide, was synthesized in Complex 1 crystallizes in the monoclinic system, space group P21 / n with a = 12.8286 (10), b = 16.3573 (13), c = 19.0206 (14) 108.2920 (10) o, V = 3789.6 (5) 3, Z = 4, Mr = 833.17, Dc = 1.460 g / cm3, μ = 0.843 mm-1, F wR = 0.0640 for 3836 observed reflections with I> 2σ (I). In the molecular structure of 1, the NiII atoms are six-coordinated by two N and two O atoms from two Schiff base ligands (L1) and two N atoms from two The cytotoxic activities of complex 1 have been experimentally studied against a human HeLa cell in vitro.