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以往在卵巢癌细胞遗传学方面的研究主要观察肿瘤细胞染色体,而对肿瘤患者全身染色体的稳定性研究较少。此外,卵巢癌除手术治疗外,化学药物治疗也很重要,所用药物大多是很强的诱变剂,它们对患者遗传物质的影响如何,过去在国内外这方面报道不多。特别是同时采用 SCE 和染色体畸变二项指标系统观察卵巢癌患者在疾病不同阶段的变化,尚未见报道。本研究的目的在于:1.观察卵巢癌患者外
Previous studies in ovarian cancer cytogenetics have focused on the observation of tumor cell chromosomes and less on the stability of whole body chromosomes in cancer patients. In addition, in addition to surgical treatment of ovarian cancer, chemotherapy is also very important, most of the drugs used are strong mutagens, their genetic material in patients with how, in the past few reports at home and abroad. In particular, the use of SCE and chromosomal aberration binomial indicator system to observe changes in patients with ovarian cancer at different stages of the disease has not been reported. The purpose of this study is: 1. Observe ovarian cancer patients outside