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吸烟与消化性溃疡形成有关,亦可影响溃疡愈合,增加溃疡复发。其机理未知,动物和人类表皮生长因子(EGF)是唾液里的一种多肽,可促使上皮增生,防止粘膜急性损伤和促进胃、十二指肠溃疡愈合。本文旨在研究吸烟与 EGF分泌减少的关系。病人和方法选用最近26个月内进行内镜检查的病人,在禁食状态下进入本研究,记录病人的年龄、性别、吸烟状况(吸烟者、已戒烟者、从来不吸烟者)、用药情况和病史,并根据现在或以往的内镜检查结果,把病人分为胃溃疡、十二指肠溃疡、食管溃疡、良性食管狭窄和无上
Smoking and peptic ulcer formation, also can affect ulcer healing, increased ulcer recurrence. The mechanism is unknown, animal and human epidermal growth factor (EGF) is a polypeptide in saliva, can promote epithelial hyperplasia, prevent mucosal acute injury and promote gastric and duodenal ulcer healing. This article aims to study the relationship between smoking and decreased EGF secretion. Patients and Methods Patients who underwent endoscopy within the last 26 months were enrolled in this study under fasting conditions and their age, sex, and smoking status (smokers, ex-smokers, never smokers), and medication were recorded And medical history, and according to the present or past endoscopic findings, the patient is divided into gastric ulcer, duodenal ulcer, esophageal ulcer, benign esophageal stricture and supreme