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对４０例原发性高血压患者采用２４小时动态血压监测方法对β受体阻滞剂（比索洛尔、阿替洛尔）进行降压疗效的比较。结果显示：２种药物均能达到全天的降压疗效；比索洛尔２４小时对收缩压及舒张压的降压作用强于阿替洛尔；比索洛尔２４小时中对舒张压降低的百分率明显强于收缩压，并能在夜间保持持续降压状态；２种药物对心率的降低无差异性。这提示，比索洛尔的降压疗效（２４小时１次口服）优于阿替洛尔。
40 patients with essential hypertension using 24-hour ambulatory blood pressure monitoring of β-blockers (bisoprolol, atenolol) to compare the efficacy of antihypertensive. The results showed that all the two drugs can achieve the antihypertensive effect all day; bisoprolol 24 hours on systolic and diastolic blood pressure is stronger than atenolol; bisoprolol 24 hours on the reduction of diastolic blood pressure percentage Significantly stronger than the systolic blood pressure, and to maintain sustained pressure at night state; 2 drugs to reduce the heart rate was no difference. This suggests that antihypertensive efficacy of bisoprolol (oral once every 24 hours) is superior to atenolol.