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目的通过调查《中国综合临床》著者稿件在表达形式上出现的问题,分析其在临床研究的设计及实施统计分析过程中存在的一些缺陷,作为医学期刊编辑对医学稿件的学术质量进行评定和指导作者修改的依据之一。方法对《中国综合临床》近3个月的稿件(自然投稿1557篇)符合分析统计要求的309篇按照①研究目的;②研究设计的科学性;③统计学的应用等临床研究的基本要素进行分析。结果统计结果显示,本次分析的309篇著者稿件中有明确研究目的者227篇,占73.46%。入选病例有诊断标准者193篇,占62.46%;研究对象的纳入和排除标准均有者66篇,占21.36%;设立对照、应用随机化且经均衡性检验三原则均具备者107篇,占37.68%。试验方法描述具体者211篇,占68.28%1有统计学处理者278篇,占94.56%。结论临床医学稿件的表达中,研究对象的选择问题较为突出,绝大多数临床研究设计缺乏科学性。提示医学期刊编辑在审定和修改稿件时应引起注意。
OBJECTIVE: To investigate the problems that arise in the manuscripts of “China’s comprehensive clinical” manuscripts and to analyze some shortcomings in the process of statistical analysis of clinical research design and implementation, and to evaluate and guide the academic quality of medical manuscripts as editors of medical journals One of the basis for the author to modify. Methods A total of 309 articles meeting the statistical requirements of analysis were collected for the manuscripts (1557 articles submitted in the nature) of the “General Clinical Clinical Program of China” in the recent 3 months according to ① research purposes; ② the scientificity of research design; ③ the application of statistics and other basic elements of clinical research analysis. Results The statistical results show that there are 227 articles with clear research purpose, accounting for 73.46% of the 309 articles submitted by this analysis. A total of 193 cases were selected as diagnostic criteria, accounting for 62.46%. 66 subjects were included and excluded, accounting for 21.36%. 107 control subjects were employed and 107 subjects were both randomized and balanced. 37.68%. Totally 211 test articles were described, accounting for 68.28% 1 There were 278 statistical tests, accounting for 94.56%. Conclusion In the expression of clinical manuscripts, the selection of research objects is more prominent, and the vast majority of clinical research designs are not scientific. It is suggested that medical journal editors should pay attention to validating and modifying manuscripts.