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目的探讨血浆中脑钠肽(BNP)浓度在心力衰竭诊断、分级和预后判断中的应用价值。方法应用免疫荧光测定法检测健康对照组、呼吸困难患者、心力衰竭患者血清BNP水平,并进行比较。结果 :心力衰竭组患者BNP水平明显高于呼吸困难患者和健康对照者(P<0.05),随着心衰程度的加重,患者血浆BNP浓度逐渐升高(P<0.05)。结论血清BNP的含量与心力衰竭高度相关,对心力衰竭诊断、判断其严重程度及预后都有十分重要的应用价值。
Objective To investigate the value of plasma brain natriuretic peptide (BNP) in the diagnosis, classification and prognosis of heart failure. Methods The levels of serum BNP in healthy control group, dyspnea patients and heart failure patients were detected by immunofluorescence assay and compared. Results: BNP levels in patients with heart failure were significantly higher than those in patients with dyspnea and healthy controls (P <0.05). Plasma BNP levels gradually increased with the severity of heart failure (P <0.05). Conclusions Serum BNP level is highly correlated with heart failure, and it has very important value in diagnosing heart failure, judging its severity and prognosis.