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膀胱癌是泌尿外科最常见的恶性肿瘤,其发病的遗传免疫学因素近年来颇受人们的重视。本文利用人白细胞抗原A复合物(简称HLA)这一遗传免疫学标志,进行了HLA与膀胱癌关联的分析,以探讨HLA与膀胱癌易感性的关系。资料和方法采用上海中心血站提供的HLA分型血清盘,应用微量淋巴细胞毒性试验进行膀胱癌患者和对照人群血液标本的HLA-A、B分型。实验组膀胱癌65例,男性46例,女性19例,年龄38～75岁。在我院经手术或电切治疗,均经病理确诊为膀胱移行细胞癌。正常对照组为随机选择的
Bladder cancer is the most common malignant tumor in urology. The genetic and immunological factors of its onset have received considerable attention in recent years. In this paper, we used the genetic immunological markers of human leucocyte antigen A complex (abbreviated as HLA) to analyze the association between HLA and bladder cancer to explore the relationship between HLA and bladder cancer susceptibility. Data and Methods The HLA-type serum plate provided by the Shanghai Central Blood Station was used. The HLA-A and B subtypes of blood samples from bladder cancer patients and control subjects were analyzed by micro-lymphocyte toxicity test. In the experimental group, there were 65 cases of bladder cancer, 46 males and 19 females, aged 38-75 years. In our hospital by surgery or electrocution treatment, were diagnosed by pathology as transitional cell carcinoma of the bladder. The normal control group was randomly selected