神经纤维瘤病是常见的遗传病,分8个亚型,最常见的是Ⅰ型和Ⅱ型,其基因定位于17号和22号染色体。Ⅰ型的特征是有虹膜结节,1937年由Lisch作出诊断,里氏结节通常为多个分布在虹膜上,有些在裂隙灯下才能看见,常聚集在虹膜收缩轮和虹膜缘,边界清晰,呈圆形或卵圆形,部分呈多环状融合,凸起的结节位于虹膜前面,用斜照法清楚地看到从虹膜水平凸出的结节阴影,结节越大,沉积的色素越 Neurofibromatosis is a common genetic disease, divided into eight subtypes, the most common type Ⅰ and type Ⅱ, the gene located on the 17th and 22nd chromosomes. Type I is characterized by iris nodules, diagnosed by Lisch in 1937, Lee’s nodules are usually distributed on the iris, and some can be seen under the slit lamp, often gathered in the iris contraction wheel and iris margin, the border is clear , Was round or oval, part of the multi-ring fusion, the raised nodules in front of the iris, with oblique method clearly seen from the iris level protruding nodules shadow nodules, the larger the deposition Pigment more