【目的】探讨小儿脑性瘫痪合并癫痫的临床特点及危险因素,为有效治疗提供参考依据。【方法】对522例脑性瘫痪患儿(合并癫痫92例,无合并癫痫430例)的高危因素、影像学资料等进行回顾性分析,并对合并癫痫的92例从临床发作特点、瘫痪类型及智力发育水平进行分析。【结果】522例脑瘫患儿合并癫痫的发生率是17.6%。低出生体重、颅内出血可作为小儿脑性瘫痪合并癫痫的危险因素(χ2=6.564和11.797,P均<0.05),而早产、窒息、黄疸两组间比较无统计学意义(P>0.05)。在影像学检查结果中,脑软化灶及脑结构畸形为癫痫的预测风险因子(χ2=5.250和14.020,P均<0.05),而脑发育不良、脑室扩大两组间比较差异无统计学意义(P>0.05)。癫痫的发作类型以强直阵挛发作最常见(44.5%),肌阵挛发作(28.3%)居第二位。97.7%的脑瘫合并癫痫患儿有不同程度的智力低下,四肢瘫患儿癫痫发病率最高(61.9%)。【结论】出生低体重、颅内出血患儿,以及四肢瘫合并智力发育落后、脑结构异常者发生癫痫的风险增高,临床应给予重视。 【Objective】 To investigate the clinical features and risk factors of cerebral palsy complicated with epilepsy in children and provide reference for effective treatment. 【Methods】 A total of 522 children with cerebral palsy (92 with epilepsy and 430 without epilepsy) were retrospectively analyzed for the risk factors and imaging data of 92 children with epilepsy. The clinical features, paralysis type And mental development level analysis. 【Results】 The incidence of epilepsy in 522 children with cerebral palsy was 17.6%. Low birth weight, intracranial hemorrhage can be used as a risk factor for children with cerebral palsy complicated epilepsy (χ2 = 6.564 and 11.797, P <0.05), while no significant difference between preterm, asphyxia and jaundice (P> 0.05). In the imaging findings, cerebral softening and brain structural abnormalities were predicted risk factors for epilepsy (χ2 = 5.250 and 14.020, P <0.05), while there was no significant difference between the two groups in brain dysplasia and ventricular enlargement P> 0.05). Epilepsy seizure type with tonic clonic seizures the most common (44.5%), myoclonic seizures (28.3%) in second place. 97.7% of cerebral palsy children with epilepsy have different levels of mental retardation, the highest incidence of epilepsy in children with tetany (61.9%). 【Conclusions】 Children with low birth weight and intracranial hemorrhage, as well as children with limbs paralysis and mental retardation, who have abnormal brain structure, have an increased risk of epilepsy and should pay more attention to it.