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幽门螺杆菌（Hp）被公认为是慢性胃炎、消化性溃疡的主要致病因素，并且与胃癌的发生密切相关。WHO将其归为第一类致癌因子[1]。但Hp的致病机制尚不十分清楚，本文就近年来有关Hp致病机制的研究近况作一介绍。1Hp相关毒力基因Hp的毒力因子有鞭毛的动力、粘附因子、脂多糖、尿素
Helicobacter pylori (Hp) is recognized as the main causative agent of chronic gastritis and peptic ulcer, and is closely related to the occurrence of gastric cancer. WHO classified it as the first type of carcinogenic factor [1]. However, the pathogenesis of Hp is not yet fully understood. In this paper, recent research on the pathogenesis of Hp is introduced. 1Hp virulence factor Hp virulence factor flagella motility, adhesion factor, lipopolysaccharide, urea