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目的:观察地塞米松鼓室内注射治疗糖尿病合并突发性耳聋的治疗效果。方法:对40例突发性耳聋患者(均为单耳)随机分成两组,实验组21例,对照组19例。两组都给以0.9%氯化钠注射液250ml+银杏叶提取物注射液25ml和0.9%氯化钠注射液100ml+单唾液酸四己糖神经节酐酯40mg,静脉滴注。实验组给以地塞米松鼓室内注射,每次5mg/ml,0.5ml,隔日一次,共5次。观察治疗前后两组患者的平均听阈。结果:实验组治愈8例,有效9例,有效率80.95%,对照组治愈5例,有效5例,有效率52.63%,两组有效率比较差异有统计学意义(P<0.05)。实验组未出现鼓室内感染,鼓膜穿孔和听力下降。结论:鼓室内注射地塞米松治疗突发性耳聋合并糖尿病是安全有效的,耳内镜下鼓室内注射具有定位准确,给药精准,安全等优点,治疗效果良好。
Objective: To observe the therapeutic effect of intravenous dexamethasone in treating diabetic patients with sudden deafness. Methods: Forty patients with sudden deafness were randomly divided into two groups: experimental group (21 cases) and control group (19 cases). Both groups were given 0.9% sodium chloride injection 250ml + Ginkgo biloba extract injection 25ml and 0.9% sodium chloride injection 100ml + monosialic acid tetrahexose ganglion anhydride ester 40mg, intravenous infusion. Experimental group to dexamethasone drum indoors, each 5mg / ml, 0.5ml, every other day, a total of 5 times. The mean hearing threshold of both groups before and after treatment was observed. Results: In the experimental group, 8 cases were cured, 9 cases were effective, the effective rate was 80.95%, 5 cases were cured in the control group, 5 cases were effective and the effective rate was 52.63%. The difference between the two groups was statistically significant (P <0.05). The experimental group did not appear typhoon infection, tympanic membrane perforation and hearing loss. CONCLUSION: Intra-tympanic injection of dexamethasone is safe and effective in the treatment of sudden deafness combined with diabetes mellitus. The intra-tympanic intrathecal injection has the advantages of accurate positioning, precise administration, safety and so on. The treatment effect is good.